?
2011-01-22 13:14:16 UTC
When annotating a DNA sequence with gene structures (i.e. promoter, exon, intron, polyA tail...etc), this often depends on computational probabilistic models.
In the beginning, when scientists have very little sequences between species to compare, the methods don't use evolutionary information to make predictions. (For example: Genscan, J. Mol. Biol. (1997) 268, 78±94)
But now as we have more species sequences available, there are now methods that use evolutionary conservation to make better predictions. (For example: Evogene Biofinromatics Vol. 19 no. 2 2003
Pages 219–227). And the result is that programs that harness evolutionary mutation rates information tend to make better performance compared to those that don't.
So my question is: if evolutionary is wrong, then shouldn't those evolutionary models fail? Yet their performance suggests otherwise.
Any comments, creationists/Christians who don't believe in evolution?
*btw I'm not forcing evolution down your throat, but just raising an issue that you probably have not thought about before